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December 20, 1913


JAMA. 1913;61(25):2237-2238. doi:10.1001/jama.1913.04350260035012

Although the subject is outside my specialty, the rarity of the disease and the lack of knowledge concerning it justify me in reporting the following case:

Family History.  —Patient's father is alive and well, active physically and mentally. The mother died of hemorrhage following some abdominal operation, at the age of 28. Father and mother were first cousins. Patient's father married again and none of the children by the second marriage are afflicted with the patient's disorder. The patient's paternal grandfather died at the age of 60 of spinal meningitis, and his paternal grandmother died aged about 35, from causes unknown to the patient. The maternal grandfather is alive and well, though slightly troubled with asthma, and the maternal grandmother died at the age of 55 from causes unknown to the patient. The patient's mother suffered from a disorder similar to his. This is shown by the disinclination she manifested

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