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Article
December 27, 1913

RESULTS OF STAPHYLOCOCCUS SPRAY TREATMENT IN FORTY-TWO CASES OF DIPHTHERIA CARRIERS

Author Affiliations

NEW CASTLE, PA.

JAMA. 1913;61(26):2293-2294. doi:10.1001/jama.1913.04350270011004
Abstract

Since diphtheria antitoxin has come into general use, quarantine of diphtheria cases is especially irksome. The patient is apparently perfectly well in a few days and the members of the quarantined family think that they are needlessly oppressed. The fact, remains, however, that although the use of antitoxin results in a speedy disappearance of all symptoms, nevertheless the diphtheria organisms may still be found in the throat, and are just as likely to infect others as they were when the patient was sick.

It is impossible to tell from the ordinary examination by culture whether the bacilli are virulent or not, and as animal inoculation is not usually possible in municipal laboratories, the quarantine is sometimes continued until the germs disappear from the throat, two or three negative cultures being required for release. This sometimes extends the period of quarantine for several weeks and it becomes a severe hardship

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