—A boy, aged 10, was brought to the Providence Psychiatrical Dispensary for general mental backwardness. He was the first born child. He was followed by a brother born at about the eighth month, who died when 2 weeks old. The next birth was a miscarriage, after which there were no more pregnancies. Venereal disease in the father or mother was denied. The family history of the father was negative. On the mother's side there was a history of various abnormalities. Her father had four brothers and three sisters, two brothers and two sisters being normal, while the other two brothers were described as having deformities of the feet, one of them also having some kind of convulsive seizures; and the other sister went blind at about 30. The mother of the patient was one of seven normal children. She had one maternal aunt and five maternal uncles, all normal.
MADIGAN JJ, MOORE TV. DYSTROPHIA ADIPOSOGENITALIS (FRÖHLICH'S SYNDROME): REPORT OF CASE. JAMA. 1918;70(10):669–671. doi:10.1001/jama.1918.02600100007003
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