The necessity for fresh guinea-pig serum and fresh sheep corpuscles in the original Wassermann technic renders that test impracticable unless these two factors are obtainable in the laboratory. I have already introduced a procedure in which the test is made possible without the use of fresh sheep corpuscles, and this antihuman hemolytic method has found wide adoption, notably in the laboratories of the United States Army and Navy. This test, however, still requires the use of fresh guinea-pig serum as complement. Considerable apprehension is being felt at present with regard to the availability of guinea-pigs and sheep to supply the necessary material for carrying out the serodiagnostic test for syphilis according to the methods hitherto in use, and a method which renders the test independent of these resources should be welcome at this time, when economy of labor, expense and time is particularly urgent. That such a method is possible,
NOGUCHI H. A METHOD OF FACILITATING THE SERUM DIAGNOSIS OF SYPHILIS UNDER WAR CONDITIONS. JAMA. 1918;70(16):1157–1158. doi:https://doi.org/10.1001/jama.1918.26010160013007c
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: