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May 25, 1918


JAMA. 1918;70(21):1536. doi:10.1001/jama.1918.02600210026009

The recognition of the Endameba histolytica as the cause of that form of dysentery known as amebic dysentery, a disease endemic in many parts of the world and liable to occur in widespread, fatal epidemics, has been helpful in many ways. The identification of the parasite and its differentiation from other organisms at times inhabiting the alimentary tract of man has made the early accurate diagnosis of the infection more easy. It has also facilitated the problems of prophylaxis and therapy by furnishing dependable information respecting the specific form of life that must be combated.

The most familiar specific therapy of amebic dysentery in recent years involves the use of ipecac and emetin. Thus, according to the Handbook of Therapy:1

Whether the amebae are on the surface of the mucous membrane, deeply embedded in the ulcers, or localized elsewhere in the body, they may be reached by properly administering