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Article
June 15, 1918

A BACTERIAL TOXIN AS THE CAUSE OF RETINAL HEMORRHAGE

JAMA. 1918;70(24):1813-1815. doi:10.1001/jama.1918.02600240009003
Abstract

In the summer of 1917, a case of retinal hemorrhage came under my observation which illuminated the heretofore obscure etiology of this condition. It made definite that which, in such conditions before, had been vague. It determined causes which could be corrected, and it made precise, measures of treatment which before had been speculative. Its importance, therefore, would seem to warrant a brief report with the deductions to which it gives rise. It is briefly as follows:

A woman in middle life had been having a series of recurrent hemorrhages in the retina for a period of eight months. During this time she had been under the advice and observation of an excellent internist and an ophthalmologist of international reputation. The treatment, therefore, might reasonably be accepted as fairly expressive of that which the best professional skill would approve. It consisted of elimination through the kidneys by saline cathartics and

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