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August 17, 1918


JAMA. 1918;71(7):592. doi:10.1001/jama.1918.02600330090025

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To the Editor:  —I am strictly in favor of the agitation which has for its purpose the replacement whenever possible of potassium salts by the corresponding sodium salts. Whenever the corresponding potassium and sodium salts are equivalent in their action, the sodium salt is practically always preferable. It is less depressing and less irritating to the gastro-intestinal tract.There is, however, one exception. And that is the iodid. I would consider it a calamity if physicians were induced to use on their tertiary syphilitic patients sodium iodid instead of potassium iodid.It is a truism to say that a salt does not merely present the sum of actions of its component elements or ions. Chlorin in combination with hydrogen does not have the same effect as chlorin in combination with sodium. And iodin in combination with sodium has not the same effect as iodin in combination with potassium. Though the

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