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August 17, 1918

Cancer: Its Nature, Causes, Diagnosis and Treatment.

JAMA. 1918;71(7):594. doi:10.1001/jama.1918.02600330092034

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This book discusses certain features of the topics mentioned in the title, for the most part conventionally, superficially and incompletely. The chief new matter is the emphasis laid on the observation by Dr. J. A. Killian that in the blood of cancer patients the total nonprotein sulphur content rises to two or three times the normal figure, while the total sulphates remain at the normal level. The urine shows an increase in the neutral sulphur compared to the oxidized sulphur, but the total amount of sulphur excreted is diminished. Considerable speculation as to etiology and treatment is indulged in on the basis of these changes in sulphur metabolism.

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