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November 9, 1918


Author Affiliations


JAMA. 1918;71(19):1534-1537. doi:10.1001/jama.1918.02600450010003

Fractional gastric analysis has for its purpose the determination of the evolution of gastric digestion. The necessity for such extended technic is justified by the fact that gastric digestion is marked by a series of constantly changing phases, so that it may now be definitely stated that an examination of any single phase of the digestive curve gives no information as to what has preceded or what will follow that phase. The most marked changes may occur in comparatively short intervals, so that findings at one period may be doubled or tripled at another period. The main point, however, is the essential fact that gastric digestion is the response of the organ to a definite stimulus, which, in health, evolves in a perfectly methodical and coordinated manner, and in disease evolves with every possible variation. In order, therefore, to interpret gastric disease, we must study the elements governing the response

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