This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
The necessity for accurate, controlled observations on preparations that are used as prophylactic agents for influenza is our reason for presenting the subjoined data.
The bacterial vaccine used in the present investigation was kindly furnished by Dr. F. O. Tonney, chief of the laboratory of the Chicago Health Department. While we are not intimately acquainted with the process of the preparation of the vaccine, we believe that it is an agent that should exhibit the immunizing properties, if any exist, of the micro-organisms used in its preparation.
Each cubic centimeter contains, approximately:
Two or more strains of each organism were used.
The dose used was 0.5 c.c. at the first injection, 1 c.c. at the second and 1.5 c.c. at the third. The interval between the injections was forty-eight hours.
The persons vaccinated were patients at a state institution for the insane. Only patients of 41 years of age or
McCOY GW, MURRAY VB, TEETER AL. THE FAILURE OF A BACTERIAL VACCINE AS A PROPHYLACTIC AGAINST INFLUENZA. JAMA. 1918;71(24):1997. doi:https://doi.org/10.1001/jama.1918.26020500023006i
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: