The consideration of asthma as a reflex from nasal disease has been a matter of interest to all of us for many years, primarily because of clinical results that are sometimes obtained by its treatment, and also because of the scientific interest we have in its problems.
This chapter of medicine was an enigma to me until the past few years: none of the observations published seemed to explain the mechanism of the disease.1 Now, the question seems to me to present possibilities, if not of solution, certainly of interesting speculation. These ideas came to me in the course of my observations on the "lower half" headache2 produced in sphenoidal and nasal ganglion lesions.
To my mind, the explanation of the pain produced from the nasal (sphenopalatine-Meckel's) ganglion, necessitates the assumption of functions on the part of the sympathetic nervous system which cannot be proved, according to the
SLUDER G. ASTHMA AS A NASAL REFLEX. JAMA. 1919;73(8):589–591. doi:10.1001/jama.1919.02610340021006