The scope of this investigation of the effect of duodenectomy in dogs is twofold: (1) to determine whether the duodenum is absolutely necessary to life, and (2) to determine its rôle in the functioning of the gastro-intestinal canal.
From a practical surgical standpoint, duodenectomy is probably of very little consequence, although several partial resections have been performed satisfactorily. From the physiologic point of view, however, the operation is significant. The duodenum occupies a very important anatomic and physiologic position just distal to the stomach, and is seemingly intimately associated with the physiology of that organ, with special reference to its mechanism for emptying. The liver and pancreas discharge their secretions into the duodenum, which bears some relation to the manner in which these organs functionate. In addition to this, the duodenum itself elaborates a secretion and contains glands (Brunners) which are found only in this part of the body. It
MANN FC, KAWAMURA K. AN EXPERIMENTAL STUDY OF THE EFFECTS OF DUODENECTOMYA PRELIMINARY REPORT. JAMA. 1919;73(12):878–880. doi:10.1001/jama.1919.02610380004003
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