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Article
October 25, 1919

UROBILIN AND UROBILINOGEN OF STOOL AND URINE IN PERNICIOUS ANEMIATHEIR VALUE IN DIAGNOSIS AND PROGNOSIS

JAMA. 1919;73(17):1262-1264. doi:10.1001/jama.1919.02610430010004
Abstract

The material for this study consisted of twenty-seven cases of pernicious anemia, and as pathologic controls nine miscellaneous conditions which included one case each of chlorosis, carcinoma ventriculi, purpura, familial hemolytic icterus, Banti's disease, lymphosarcoma, acute cholecystitis, hemochromatosis, and tabes dorsalis.

The method was a modification of Wilbur and Addis'1 spectroscopic method. The modification was instrumental and has been described recently by J. D. Boyd,2 working in our laboratory under the direction of Dr. Louis Baumann. The instrument "was constructed from a Hellige colorimeter and a hand spectroscope and consisted essentially of a hollow glass wedge which can be moved vertically before a fixed spectroscope" (8 cm.). The sample is prepared in the usual manner. "The cell, which holds about 10 c.c., is filled with the solution, and the point is found when the spectrum just disappears with moderate light3 but reappears when the light is diminished by

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