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October 25, 1919


JAMA. 1919;73(17):1288-1289. doi:10.1001/jama.1919.02610430036015

Much of the recent progress in the science of nutrition is directly attributable to the results of experiments on the lower animals. More recently, the dog, cat and rabbit, long classic subjects of feeding trials, have been replaced by smaller species, including the mouse, rat, guinea-pig and pigeon. How large a part these animals have played in establishing the rôle of vitamins in the diet, readers of The Journal have had repeated occasion to learn. Yet whenever a research, concluded through the use of some single species for investigation, brings some striking new fact of nutrition, one almost instinctively asks whether the finding is of more general application, particularly in the case of the human animal.

Lately scurvy has been the subject of lively interest among investigators. Definite symptoms, resembling in several details those found in infantile scorbutus, can be induced in the guinea-pig by dietary deficiencies. Most striking thus