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November 29, 1919

A BACTERIOLOGIC INVESTIGATION OF AN OUTBREAK OF INFLUENZA IN AN INSTITUTIONTHE INMATES OF WHICH WERE PREVIOUSLY FREE FROM THE INFLUENZA BACILLUS WHEN COMPLETELY VACCINATED WITH INFLUENZA VACCINE

JAMA. 1919;73(22):1657-1658. doi:10.1001/jama.1919.02610480007004

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Abstract

The New York State Training School for Girls at Hudson, N. Y., is located on the southern outskirts of the city. The population of Hudson was 11,544 in 1915. It accordingly ranks as a third-class city. Early in the influenza epidemic in this country there was an outbreak in Hudson, but the quarantine that was immediately established at the training school was so rigidly and so effectively carried out that no cases of influenza developed in the institution. In order further to safeguard the inmates, all were vaccinated. A vaccine prepared by suspending in salt solution the growth of fifteen strains of the influenza bacillus (a vaccine prepared by the central laboratory at Albany, and one used generally throughout the state) was the vaccine used. Three doses containing 1 billion bacilli per cubic centimeter were given, a first dose of 0.5 c.c., and the second and third doses of 1

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