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November 29, 1919


JAMA. 1919;73(22):1691-1692. doi:10.1001/jama.1919.02610480041012

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Nonspecific urethritis has been defined by Keyes as "an acute urethritis due neither to the gonococcus nor tubercle bacillus and usually excited by no known cause other than sexual excitement or contact." He states further that it is almost, but not quite, universally true that the normal male urethra is immune to infection by any bacterium except the gonococcus. The observation of the bacteriologic findings in a vast number of cases of urethritis, and the not infrequent occurrence of cases in which the discharge failed to show the presence of gonococci, prompted a careful study and analysis of such cases.

Just how frequently this condition occurs is rather difficult to state, since no record of the total number of cases examined is available; however, the twenty-eight cases presented herewith appeared in two different localities during a period of slightly less than five months, and were encountered during the examination of

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