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Article
December 6, 1919

CAROTINEMIA: A NEW CLINICAL PICTURE

JAMA. 1919;73(23):1743-1745. doi:10.1001/jama.1919.02610490007003
Abstract

About a year ago one of us (A. F. H.) observed that two children in a ward containing about twenty-five infants, from a year to a year and a half in age, were developing a yellowish complexion. This coloration was not confined to the face, but involved, to a less extent, the entire body, being most evident on the palms of the hands, which showed also distinct signs of desquamation. The sclerotics were not at all affected. The urine was amber, and the stools normally yellow. For a time, we were at a loss to account for this peculiar phenomenon, when our attention was directed to the fact that these two children, and only these two, were receiving a daily ration of carrots in addition to their milk and cereal. For some time we had been testing the food value of dehydrated vegetables, and when the change in color was

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