[Skip to Content]
[Skip to Content Landing]
December 13, 1919


JAMA. 1919;73(24):1828-1832. doi:10.1001/jama.1919.02610500018006

This report is based on the study of thirty men in whom the physical findings were suggestive of hyperthyroidism. They had rapid pulse, enlargement of the thyroid gland, fine tremor of the hands, moist, clammy palms, and some of the eye signs usually associated with exophthalmic goiter. The object of the observations was to determine if possible whether the thyroid gland was the basis of these physical findings.

METHOD OF STUDY  In addition to the usual routine physical examination and laboratory work, blood sugar determinations were made following the administration of glucose by mouth. The response to epinephrin and the effect of thyroid feeding were also noted.

Technic of the Sugar Tolerance Test.  —The test was made in the same manner as that recently described by Janney and Isaacson1 except that the blood sugar determinations were made by the Lewis-Benedict method.2 The patient was not allowed breakfast. About