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Article
December 20, 1919

COMPLEMENT FIXATION TEST FOR TUBERCULOSIS

JAMA. 1919;73(25):1879-1882. doi:10.1001/jama.1919.02610510017009
Abstract

In this series, 466 cases were studied. The final diagnosis was: pulmonary tuberculosis, including suspects, 220; extrapulmonary tuberculosis, 13; nontuberculous, 233.

METHODS EMPLOYED  All patients were first given a general examination by the internist who referred them to us for intensive study of the lungs on account of pulmonary physical findings, the past history, or present suggestive symptoms.The clinical chest study by Pritchard consisted of a careful history, a physical and fluoroscopic examination with an interpretation of stereoscopic plates of the chest, and three sputum tests as well as a three days' pulse and temperature observation.The serologic study by Roderick consisted of a Wassermann test with both cholesterin and acetone antigens, and a complement fixation test with two antigens for tuberculosis.The work was finished separately and charted. The physical findings were recorded before the roentgenographic interpretations were made. In no case did the laboratory have any information

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