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There is on foot a world-wide campaign for the control and suppression of syphilis. The medical profession is in accord in its belief that the best remedies for this disease are the new organic arsenicals and mercury. No one has yet evolved a crystallized formula for the treatment of syphilis which has been generally accepted. There are many standards of treatment, but no standard. Different authorities have their individual preferences as to the strength of the dose of the arsenicals, the frequency of administration, the duration of the course, and the choice of the compound to be employed. In other words, the medical profession is groping to find a therapeutic procedure which will combine safety and maximum efficiency. The trend of the best opinion is to make the treatment, particularly in the early stages, as intensive as is consistent with safety. The curability of syphilis is, in general terms, directly
Schamberg JF. ARSPHENAMIN VERSUS NEO-ARSPHENAMIN. JAMA. 1919;73(25):1883. doi:10.1001/jama.1919.26120510001011
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