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Comment & Response
May 19, 2015

Treatment for Clostridium difficile Infection in Adults

Author Affiliations
  • 1Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada
JAMA. 2015;313(19):1974-1975. doi:10.1001/jama.2015.3668

To the EditorClostridium difficile infection is a common, serious diarrheal illness, and strains such as the virulent North American pulsed-field gel electrophoresis type 1 make treatment challenging. The meta-analysis1 summarizing the available treatment options for incident C difficile infection in adults recommended vancomycin with or without adjunctive therapy as the treatment of choice for severe, complicated infections and metronidazole for milder disease.