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August 5, 1922

EXPERIMENTAL STUDIES ON THE ETIOLOGY OF ENCEPHALITIS: REPORT OF FINDINGS IN ONE CASE

Author Affiliations

ROCHESTER, MINN.

From the Division of Experimental Bacteriology, Mayo Foundation.

JAMA. 1922;79(6):443-448. doi:10.1001/jama.1922.02640060025008
Abstract

It has been my privilege to study the etiology of encephalitis during the past three years through the cooperation of Dr. Shelden and his associates of the Section on Neurology of the Mayo Clinic. From the outset of this study it was considered possible that the disease might be caused by a filtrable virus or by bacteria of more ordinary morphology but with peculiar neurotropic properties. The methods employed were such as to test both possibilities. Altogether, forty cases, representing different clinical types of the disease, have been studied. A large number of animals have been injected; the microscopic study of sections is not yet completed, and other details in the mass of experimental data are awaiting final analysis.

In order to illustrate in general the scope of the work and the results obtained, I shall report at this time in some detail the findings in one case.

Mrs. P.

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