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This follows the lines of former editions. While there have not been many changes or additions, yet the extended personal experience of Boas with the Wassermann test has enabled him to draw valuable conclusions concerning the test. After a rather comprehensive historical review, Boas discusses the technic and details of the test, and describes many of the numerous modifications. He believes the simple alcoholic extract of human or beef heart the most reliable antigen, although he inclines to the belief that the cholesterolized antigens may be of value if properly controlled to rule out false positive findings. For the sake of completeness he discusses many of the tests which have been advanced as substitutes for the Wassermann test, and believes that the Sachs-Georgi and Meinicke tests are the best of these. The special merit of this little book is the discussion, based on the personal experience of the author, of
Die Wassermannsche Reaktion mit besonderer Berücksichtigung Ihrer klinischen Verwertbarkeit. JAMA. 1922;79(6):495. doi:10.1001/jama.1922.02640060077032
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