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September 2, 1922


JAMA. 1922;79(10):815-819. doi:10.1001/jama.1922.02640100035012

Ulcerating granuloma is also known as granuloma inguinale, ulcerating granuloma of the pudenda, sclerotisizing or sclerosing granuloma of the pudenda, serpiginous ulcerations of the genitalia, granuloma inguinale tropicum, granuloma venerum, groin ulceration, chronic venereal sores and granulomatosis. It is a skin and mucous membrane disease found in the tropic, subtropic and temperate zones. It is an infectious, chronic, indurated, cicatrizing growth on or near the genitals of males and females, with no tendency to glandular involvement or serious impairment of the general health. The majority of the patients are in the period of sexual maturity. Women are said to be more frequently affected than men. The colored races have been thought to have a predisposition to this disease, but a large number of white patients have also been reported.

I have had the opportunity of studying cases of granuloma inguinale in Porto Rico and other islands of the West Indies,