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September 30, 1922

Typhoid Carriers and Typhoid Immunity. Omnis Typhus ex Typho.

JAMA. 1922;79(14):1168. doi:10.1001/jama.1922.02640140080043

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This interesting monograph is based on an elaborate and properly prolonged study of 164 cases of typhoid developing during the war in an internment camp in North Carolina. Among the many important observations is the fact that in as many as 15 per cent. of typhoid convalescents, typhoid bacilli may be discovered in the bile after three consecutive stool cultures have proved negative. The author considers that two consecutive negative bile cultures and two consecutive negative feces cultures are necessary to give an absolutely safe indication of complete absence of typhoid bacilli in the intestinal tract. Many interesting laboratory details are contained in the paper. The author found Endo medium very satisfactory for isolating the typhoid bacillus. It is to be regretted that some recent writers on typhoid, among whom the present author is one, are inclined to exaggerate the importance of typhoid at the present time in order to

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