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An opportunity to observe the effect of radium exposures over the spleen in a case of polycythemia and splenomegaly over a series of years in repeated exacerbations of the disease does not often present itself. The case reported here was observed from Jan. 26, 1917, to Sept. 10, 1923, in four distinct attacks, during which the polycythemic state became much aggravated. In three of these exacerbations, radium exposures over the spleen with or without the administration of benzene produced a profound improvement in the blood within three months following the use of the radium. The case is reported for this reason and its scientific importance.
—Mrs. V., aged 49, mother of four children, two living and two that died at delivery (twins), was examined, Jan. 26, 1917. Her mother had died of carcinoma of the stomach, and one sister had died of carcinoma of the uterus; two sisters were
Head GD. TUBERCULOSIS OF SPLEEN WITH POLYCYTHEMIA AND SPLENOMEGALY IMPROVED BY TREATMENT WITH RADIUM AND BENZENE. JAMA. 1924;83(1):40–41. doi:10.1001/jama.1924.26610010001015
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