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Article
October 14, 1922

SYPHILIS OF THE MOUTH: COMMON TENDENCY OF THE MOUTH AND SKIN TO THE SAME PATHOLOGIC PROCESSES

JAMA. 1922;79(16):1285-1289. doi:10.1001/jama.1922.02640160005002
Abstract

There is a close relation between the tissues of the mouth and those of the skin. Their structures are very much alike, and they react to many pathologic processes in the same way. There are numerous systemic diseases which have eruptions on the oral mucous membrane as well as on the skin, and these oral eruptions are identical with those of the skin, except as they are altered by the peculiar local conditions to which they are subjected in the mouth. These facts are particularly well exemplified in syphilis. The skin and the mouth are the structures for which syphilis shows its greatest predilection, and the predilection is quite as great for the mouth as for the skin. Indeed, it is probably true that syphilis occurs with as great frequency in the mouth as on the whole surface of the skin. Its frequency in the mouth, then, would of itself

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