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Instances of recovery, after failure of the heart action, by the injection of epinephrin into the heart are sufficiently rare to justify the report of a case in which this occurred:
REPORT OF CASE
S. K., a man, aged 73, with generalized arteriosclerosis, was admitted to the hospital, June 26, 1921, complaining of severe pain in the right leg due to trophic changes. The patient was in fairly good condition for his age, although there was marked emphysema of the lungs, and emaciation. The heart sounds were distant and of poor quality. The arteries of the extremities were tortuous and much thickened. There was marked atrophy of the muscles of the right lower extremity. Neither the dorsalis pedis nor the popliteal arteries could be felt. The Wassermann blood test was negative. The urine contained a trace of albumin, but no casts. The blood analysis revealed the urea nitrogen as 12.2.
JULIUS GOTTESMAN. RESUSCITATION BY THE INTRACARDIAC INJECTION OF EPINEPHRIN. JAMA. 1922;79(16):1334–1335. doi:10.1001/jama.1922.02640160054018