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October 21, 1922


JAMA. 1922;79(17):1428-1429. doi:10.1001/jama.1922.02640170054019

Some of the uncertainty with respect to the function of the gallbladder is gradually being dispelled in the light of new experiments. The traditional view that the chief activity of this organ is storage has been supported, if not actually magnified, by Rous and McMaster's striking demonstrations of how much inspissation and concentration of bile may occur in the bladder, and how dilution can subsequently be accomplished through the secretion of "white bile" by the ducts through which the thick secretion may pass. Recently, too, attention was called to the possible service that the galbladder may render in protecting the bile ducts and sphincter from undue changes in pressure within the system. How and when the bladder discharges its occasional surplus contents is not so clearly understood. The results of investigation are often difficult to interpret because of the anatomic differences between the species of animals used for experimental investigations