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Comment & Response
June 16, 2015

Presurgery Sedation and Patient Experience

Author Affiliations
  • 1Jikei University School of Medicine, Tokyo, Japan
JAMA. 2015;313(23):2379. doi:10.1001/jama.2015.5513

To the Editor In a randomized clinical trial by Dr Maurice-Szamburski and colleagues,1 premedication with oral lorazepam 2 hours prior to arriving in the operating room did not improve patient satisfaction after surgery and was associated with prolonged time to extubation and decreased cognitive recovery compared with placebo or no medication. These results may not indicate that all sedative premedication is unwarranted but may suggest lorazepam is inadequate.