This case is reported because of its unusual features.
REPORT OF CASE
Miss C. V. A., aged 21, a college student, was referred for diagnosis and treatment of asthma, March 30, 1921. Her maternal great-grandfather had asthma, her maternal uncle suffered from eczema, a maternal first cousin, once removed, had asthma, and a paternal uncle had attacks of hay-fever. She had had all the diseases of childhood, also diphtheria and tonsillitis, and influenza of moderate severity, two years previously. The adenoids had been removed in childhood. She suffered many head "colds" each winter. There was a history of some dyspnea about fifteen months before following a severe cold. This was apparently very mild. The condition now complained of had developed about three months before and had been steadily growing worse. After the last attack, she was confined to the infirmary for a few days. The attacks developed in the evening
CLARKE JA, MEYER GP. A CASE OF HYPERSENSITIVENESS TO SILK. JAMA. 1923;80(1):11–12. doi:10.1001/jama.1923.02640280013004
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