The changes in the roentgen-ray findings of peptic ulcer that take place in the course of medical treatment can be studied best in that type of ulcer showing a penetration on the lesser curvature. When filled by barium, the crater of a penetrating ulcer appears as a budlike projection from the outline of the stomach, which has been termed a "niche" by Haudek. When situated on the lesser curvature, a niche can be easily visualized, and is unlikely to be simulated by adhesions or cicatrices as are ulcers at the pylorus or duodenum.
Since Hamburger, in 1918, published his roentgenologic studies on the healing of peptic ulcers, several reports have appeared showing the diminution in size or the total disappearance of a niche in response to medical treatment. Most of the reported cases were observed for too short a time to draw definite conclusions regarding their cure, but these changes
HOLLANDER E. FALLIBILITY OF ROENTGENOLOGIC EVIDENCE OF HEALED GASTRIC ULCER: REPORT OF CASE. JAMA. 1923;80(1):29–31. doi:10.1001/jama.1923.02640280031014
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