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Article
January 13, 1923

BACTERIOLOGIC AND CLINICAL EXPERIENCE WITH BACILLUS ACIDOPHILUS

Author Affiliations

NEW HAVEN, CONN.; NEW YORK

JAMA. 1923;80(2):90-92. doi:10.1001/jama.1923.02640290020007
Abstract

Our aim was to implant Bacillus acidophilus in the intestine and, while maintaining it as the predominant intestinal organism, to determine what changes, if any, were noted clinically. To ascertain the bacteriologic facts, we examined the feces of every patient before treatment and then at intervals of from five to ten days. In all the cases mentioned later, the implantation of this organism was successful, and during treatment it became the predominating fecal organism, and we were able to recover live Bacillus acidophilus from the feces.

After infancy, milk is less prominent in the diet than during infancy. Bacillus acidophilus gradually diminishes until in adult life it is present in very small amounts. The adult intestinal flora is determined, more or less, by the diet of the individual. The accompanying illustrations demonstrate the changes in the fecal flora after the administration of B. acidophilus.

It has been our endeavor to

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