[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
February 10, 1923


Author Affiliations

From the Laboratory of the Cook County Hospital, Chicago.

JAMA. 1923;80(6):383-384. doi:10.1001/jama.1923.02640330019009

From time to time, numerous discrepancies in the Wassermann test for syphilis have been reported, and though standardization of the test has been many times attempted, no method of standardization is as yet generally accepted. To meet this difficulty, several precipitation tests have been developed, the latest and simplest being that of Kahn,1 modified by Herrold.2

The latter test is even more simple and economical than the Kahn test. It is based on the formation of a ring of precipitation of antigen when in contact with serum from a patient with syphilis. To determine the value of this precipitation reaction in the diagnosis of syphilis, parallel observations on Wassermann and precipitin tests have been made.

The antigen used was prepared according to the method described by Kahn. For the test, the antigen is diluted rapidly 1: 10 or 1: 12 with physiologic sodium chlorid solution, as outlined by