In defining renal glycosuria, Strouse1 gives four points of differentiation from diabetes mellitus: (1) glycosuria without hyperglycemia; (2) glycosuria almost entirely independent of carbohydrate intake; (3) absence of diabetic symptoms, and (4) no subsequent development of diabetes mellitus. Paullin2 has added a fifth characteristic in this condition, that sugar shall be constantly present in the urine.
That renal glycosuria shall not later become diabetes mellitus necessitates a prolonged observation of such patients, and this is the reason for reporting a case in which glycosuria was discovered eighteen years ago, the patient having been employed in a hospital for the sake of supervision for the last nine years. Bailey3 has reported a case in which glycosuria has been known for ten years, and says, "The patient's history points strongly to this being a congenital condition." Strouse has observed a case for eight years, Garrod4 and Bonninger5
Allan W. A CASE OF RENAL GLYCOSURIA. JAMA. 1923;80(7):471–472. doi:10.1001/jama.1923.26430340003011d
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