[Skip to Content]
[Skip to Content Landing]
Article
December 13, 1924

EXCISED DUODENAL ULCERS: A REPORT OF FOUR HUNDRED AND TWENTY-FIVE SPECIMENS

Author Affiliations

ROCHESTER, MINN.

JAMA. 1924;83(24):1894-1898. doi:10.1001/jama.1924.02660240008002
Abstract

From 1906 to June, 1924, there have been 425 duodenal ulcers and ninety-seven localized inflammatory duodenal areas excised at operation and studied grossly and microscopically in the Mayo Clinic.

The largest ulcer was 25 mm. in diameter, and the smallest, 1 mm.; the average diameter of the ulcers was 5.5 mm.

Four questions presented themselves in a study of this material:

  1. Are duodenal ulcers similar to gastric ulcers in gross morphology?

  2. Is there any difference between the appearance of duodenal ulcers at necropsy and at operation?

  3. What is the relation of duodenitis to duodenal ulcer?

  4. Do we find the same cytologic reactions suggesting malignancy in the tubules of duodenal ulcers that we find in gastric ulcers?

Experience with 1,269 carcinomatous gastric ulcers, 832 simple chronic gastric ulcers, 425 excised duodenal ulcers and ninety-seven excised chronically inflamed (duodenitis) portions of the duodenum reveals the following facts:

  1. Chronic gastric ulcers and duodenal

×