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March 17, 1923


JAMA. 1923;80(11):772-773. doi:10.1001/jama.1923.26430380003011a

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PRINCIPLES GOVERNING THE PREPARATION OF MILK MIXTURES  So far as it has been developed by the scientific knowledge of the present day, the basis to be recommended for the artificial feeding of average normal infants is the unit requirements in fat, protein, carbohydrate, salts, water and accessory food factors per pound or kilogram of body weight.It is therefore evident that there must be a rational understanding of the infant's digestive and metabolic processes as concerns the individual ingredients of his diet, and that the quantitative relationship of the individual components of the diet to these physiologic processes must be duly considered. It soon becomes evident that while in many instances one or more of the food elements may cause digestive disturbance, poorly balanced combinations of these elements have a far greater influence on its development. If all the ingredients are in excess, it may cause a general upset to

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