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Mr. J., aged 28, a traveling salesman, consulted a physician in a neighboring city, Nov. 10, 1921, for a small sore on the glans penis. He. was told that it was a simple infected herpes, and was given a jar of a blue colored ointment to apply. The lesion healed in about ten days. Jan. 4, 1922, he consulted us with a florid maculopapular eruption which was generally distributed over the forehead, face, trunk and extremities, with several mucous patches on the tongue and inside of the cheek. As the rash was typical, and there had been the history of a lesion, we did not think it necessary to make a Wassermann test.
Intravenous injections of 0.9 gm. of neo-arsphenamin were given, January 4, February 5, 12, 19 and 26, March 26, and April 2, 9 and 16. The patient refused to take mercury intramuscularly so was given a 50
Nichols WC, Nichols AA. A SECOND INITIAL LESION OF SYPHILIS ONE YEAR AFTER THE FIRST. JAMA. 1923;80(12):843. doi:10.1001/jama.1923.26430390003011b
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