The train of symptoms that often attend acute intestinal obstruction is familiar to every clinician. The phenomena have given rise to much speculation and also have formed the subject of repeated experimental investigation, particularly because the severity of the manifestations in many cases is so pronounced at an unexpectedly early moment after the continuity of intestinal function is interrupted that the cause has not been clearly apparent. The contradictory and contending views of workers in this field have frequently been detailed in The Journal. The mortality is high in certain types of cases, and the plan of relief a problematic one. Anhydremia, intoxication with bacterial products from obstructed intestinal loops or disintegration products of the exfoliating mucosa, hypochloremia, and shock—these and other possible factors have been drawn into explanation without, however, finding universal acceptance as a satisfactory guide to the pathogenesis of such clinical states as may be presented by
NEW LIGHT ON THE FEATURES OF ACUTE INTESTINAL OBSTRUCTION. JAMA. 1925;84(2):122–123. doi:10.1001/jama.1925.02660280048018
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