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April 14, 1923

Injury, Recovery and Death, in Relation to Conductivity and Permeability.

JAMA. 1923;80(15):1093. doi:10.1001/jama.1923.02640420055034

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The publication of this series of monographs on experimental biology is a great credit to American scholarship, and, what is of more importance, a great stimulus to the progress of biologic science. Since the medical sciences are of necessity based on biology, the furtherance of these fundamental studies is of immediate importance to medicine. The present volume is one that is of particular interest to the pathologist, for the contributions of the author to our knowledge of cell vitality mark an important step toward illuminating the most fundamental of all mysteries—What changes accompany and determine cell death. These studies are based on the observation that any injury to cells is accompanied by changes in the electrical resistance of the cells, falling steadily until a level is reached which indicates that death is complete. This makes it possible to study loss of vitality in a quantitative way, and quantitative measurements are

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