The invasion of the spinal column by syphilitic infection is less frequently encountered than syphilitic lesions in other parts of the osseous system; however, syphilitic spondylitis is now recognized as an occasional complication of syphilitic infection, and should deserve our careful consideration in the differentiation of diseases of the spine.
During the last eight years, at the Cincinnati General Hospital, there have been recorder 111 cases of syphilitic disease of the bones and joints; of these there were only nine patients who presented symptoms of syphilitic spondylitis, and one who suffered from syphilitic disease of the sacro-iliac joint. The regions of the spine involved in the nine cases of spondylitis were: lumbar, five; cervical, three, and lower dorsal, one. Of these, three were in children of 12 years and under, and six were in adults ranging in age from 25 to 64. Three patients were colored, and the remaining six
COFIELD RB, LITTLE CF. SYPHILITIC SPONDYLITIS. JAMA. 1925;84(3):174–177. doi:10.1001/jama.1925.02660290018009
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