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Clinical Trials Update
June 23/30, 2015

Osteoporosis Drug May Benefit the Frail Elderly in Nursing Homes

JAMA. 2015;313(24):2416. doi:10.1001/jama.2015.6097

A single intravenous dose of the potent osteoporosis drug zoledronic acid significantly improved bone mineral density (BMD) in frail elderly women living in long-term care facilities. Positive findings from the proof-of-concept randomized trial paves the way for an “essential” larger trial to study fracture reduction with bisphosphonate treatment in a frail elderly population. (Greenspan SL et al. JAMA Intern Med. doi:10.1001/jamainternmed.2015.0747 [published online April 13, 2015]).