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February 14, 1925


JAMA. 1925;84(7):518-519. doi:10.1001/jama.1925.02660330038015

In discussing the functions of the skin, many popular treatises on physiology and hygiene, including even those of comparatively recent date, tend to stress the protective feature and the excretory activities of the integument as the foremost items worthy of emphasis. It is true that a profuse output of perspiration carries with it a small content of inorganic salts along with a variety of organic components, some of which are ordinarily found in the urine as well as in the blood. It seems desirable, however, to give renewed prominence to the well established conviction that although the sweat may simulate the urine qualitatively, the amount of metabolic waste products or so-called catabolites in the fluid is comparatively slight. As recent writers have pointed out, the sudoriparous glands are not responsive to chemical changes in the blood, as are the kidneys; they are unable to excrete waste products in concentration; in