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February 14, 1925


JAMA. 1925;84(7):534. doi:10.1001/jama.1925.02660330054029

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To the Editor:  — In the article on this subject (The Journal, Dec. 20, 1924), statements were made by Drs. Sonnenschein and Pearlman which, unless corrected, would convey the wrong impressions.

  1. The calcium standard is given as from 9 to 11 mg. per hundred cubic centimeters of blood serum. It is neither reasonable nor scientific to establish such a wide range of normality; for, if such were the case, it would be extremely difficult to make a classification of calcium deficiency diseases. As the standard, 10.5 mg. has been commonly accepted, although this standard is of no particular significance, because, as Woringer (Hypocalcémie et spasmophilie, Arch. de méd. d. enf. 26:713, 1923) has shown in spasmophilia, hypocalcemia is more pronounced in the manifest forms of the disease than in the latent forms. Furthermore, the hypocalcemia is not in direct relationship with the gravity of the disease. Thus, the calcium deficiency

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