Syndactylism, or webbing of the digits, is a deformity seldom encountered in medical practice. The cases reported here may throw some light on the hereditary aspect of the condition. In the past, other families have been described, in many of which the component groups have been very small. This has detracted from their value to students of the hereditary aspect. In the family presented here, the groups within the whole have been large, and the deformity has occurred with considerable frequency.
The cause of the deformity is not known. Osler thought that it occurred more frequently in children of syphilitic parentage. Edwards 1 states that it is a stigma of degeneration occurring in persons of weakened intellect. He does not attempt to explain the cause of the weakened intellect. A decidedly low mentality accompanied the defect as it is presented in the family described here. What part alcohol, infection and
MURPHY DP. FIVE SUCCESSIVE GENERATIONS OF WEBBED-FINGER DEFORMITY: STUDY OF A FAMILY. JAMA. 1925;84(8):576–577. doi:10.1001/jama.1925.02660340014005
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