The occurrence of Oxyuris vermicularis in the vermiform appendix of the human species has been frequently described in the literature. The description of parasites in this structure dates back to Fabricius, in 1634, and Santorini, in 1724. Metchnikoff1 was the first to lay stress on the relationship of intestinal parasites to appendicitis. Even though many reports, chiefly of single instances, have appeared from various centers, especially abroad, over a considerable period of time, and form in their aggregate quite a voluminous literature, nevertheless, the rôle of the oxyuris as a causative factor of appendicitis has received little consideration. The reasons for such a condition are probably twofold: (1) the failure of proper clinical and pathologic observations as to the extent of their occurrence in appendical involvements; (2) the difference of opinion existing relative to the pathogenic rôle played by these nematodes in such lesions.
Unless the pathologist directs specific
WILLIAM H. HARRIS, DONOVAN C. BROWNE. OXYURIS VERMICULARIS AS A CAUSATIVE FACTOR IN APPENDICITIS. JAMA. 1925;84(9):650–654. doi:10.1001/jama.1925.02660350014003