[Skip to Content]
[Skip to Content Landing]
Article
March 7, 1925

SURVIVAL OF THE MAMMALIAN TESTIS IN VITRO

Author Affiliations

CHICAGO
From the Hull Physiological Laboratory, the University of Chicago.

JAMA. 1925;84(10):746-748. doi:10.1001/jama.1925.02660360028010
Abstract

This study was undertaken at the suggestion of Dr. Carlson with the aim of determining the length of time that may be permitted between the removal of the testis from the donor and a successful graft made into the recipient. So far as we know, in all work on testis grafting in experimental animals, immediate implantation of the excised testis has been made. In similar work on man, the testis has frequently remained for hours in the dead body of the donor, or the excised testis kept on ice for from one to thirty days before implantation, with reports of successful takes of the graft. If true, this would indicate an extraordinary survival of the mammalian testis outside the body under conditions of asphyxia, autolysis, accumulation of metabolites, and absence of nutrient material. Because of the inconclusive character of much of the clinical data, both as to the criteria of

×