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Article
March 21, 1925

MERCUROCHROME-220 SOLUBLE AND GENTIAN VIOLET: BACTERICIDAL EFFICIENCY BY INTRAVENOUS ROUTE

Author Affiliations

PORTLAND, ORE.
From the Departments of Internal Medicine and Pharmacology of the University of Oregon Medical School.

JAMA. 1925;84(12):879-881. doi:10.1001/jama.1925.02660380015004
Abstract

In March, 1924, Young and Hill1 published some very interesting results in the treatment of septicemia and local infections by intravenous injections of mercurochrome-220 soluble and gentian violet, reporting a series of twelve cases. The series was divided into two groups. The first group included seven cases of local and generalized (bacteremic) infections with either staphylococcus or colon bacillus, and one case of chronic pyelitis due to Bacillus lactisaerogenes. These patients were treated by intravenous injections of mercurochrome-220 soluble. The second group was composed of five cases of staphylococcic infection of both the local and bacteremic type, including some cases with multiple pyemic abscesses. These patients received intravenous injections of gentian violet. Cures were obtained in all twelve cases.

In June, 1924, Whitman2 reported equally remarkable results from the intravenous injections of mercurochrome in ten cases of chronic and subacute gonorrhea. He said: "The rapid subsidence of symptoms

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