The stimulation of interest in the treatment of paresis, through the work of Professor Wagner-Jauregg and others by the experimental use of malarial inoculation, led Dr. William A. White, superintendent of St. Elizabeth's Hospital, to have this mode of treatment tried at this institution. Professor Wagner-Jauregg had noticed as far back as 1887 that paretic patients had a tendency to improve following attacks of intercurrent infectious disease, and since that time had made various attempts to produce an analogous condition artificially, in the hope of obtaining the same end-result, and finally, because it could be definitely controlled, he selected the organism of benign tertian malaria for this purpose. Since his first work along this line others have made similar attempts, and reports made by Weygandt, Redlich, Mühlens, Dattner, Plehn, McAlister, Grant and contemporaries indicate a widely varying opinion as to its efficacy and general practicability. Dr. Nolan D. C. Lewis
ELDRIDGE WW, Lind JE, Silk SA, Trentzsch PJ. TREATMENT OF PARESIS: RESULTS OF INOCULATION WITH THE ORGANISM OF BENIGN TERTIAN MALARIA. JAMA. 1925;84(15):1097–1101. doi:10.1001/jama.1925.02660410005002
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