[Skip to Navigation]
Article
April 25, 1925

PELLAGRA SECONDARY TO LESIONS OF THE STOMACH INTERFERING WITH NUTRITION

Author Affiliations

SAN FRANCISCO
From the Department of Medicine, University of California Medical School.

JAMA. 1925;84(17):1250-1253. doi:10.1001/jama.1925.02660430008002
Abstract

An interesting side-light is thrown on the subject of pellagra by the occasional appearance of the disease in patients with faulty food utilization due to some gastrointestinal lesion.

The observation in the last three years of three such cases has prompted this report and a review of the subject. Pellagra developed in one of these patients during a period of jejunal feeding necessitated by deformity of the stomach by a benign ulcer, and in the other two during progressive carcinomatous pyloric obstruction. Only two similar reports have been found in the literature.

Rolph 1 saw a skin eruption, glossitis, pharyngitis and mental symptoms considered typical of pellagra coming on four months before death, in a woman who died after seven months of excessive expectoration with increasing dysphagia, vomiting and emaciation. Postmortem examination revealed a carcinoma of the stomach, which involved the cardia and, acting as a valve, mechanically interfered with

×